Abstract
Introduction: Thyroid nodules are one of the most common diseases. Objectives: The aim of this study was to evaluate the correlation between fine needle aspiration (FNA) and intraoperative frozen section findings for thyroid disease patients. Patients and Methods: In this study, the FNA and intraoperative frozen section findings of 143 patients who were admitted to an educational hospital, Isfahan, Iran were collected and classified using these diagnostic methods during 2015. To find the correlation between FNA and intraoperative frozen section findings, statistical analysis was conducted using SPSS software version 16.0 (Chicago, IL). Results: Sensitivity and specificity of the positive FNA findings were 71% and 86.8%, respectively (P<0.001). The maximum concordance between FNA and intraoperative frozen section for papillary thyroid cancer was seen (P<0.001). Conclusion: In this study, a significant association between FNA and intraoperative frozen section of thyroid cancers, among our patients, however this finding requires further investigation by larger studies.
Highlights
Thyroid nodules are one of the most common diseases
We found a significant association between fine needle aspiration (FNA) and intraoperative frozen section of thyroid cancers
In a study conducted on 42 patients with thyroid nodules, the results showed that the FNA method in the diagnosis of thyroid nodules is a more sensitive and specific method than the surgical sampling method [6]
Summary
Objectives: The aim of this study was to evaluate the correlation between fine needle aspiration (FNA) and intraoperative frozen section findings for thyroid disease patients. Conclusion: In this study, a significant association between FNA and intraoperative frozen section of thyroid cancers, among our patients, this finding requires further investigation by larger studies. In Iran, 9.5% of the adult population has a palpable thyroid nodule [1]. Thyroid nodules are solid or fluid-filled masses that form inside the thyroid and form a small gland at the base of the neck. Many of these nodules are asymptomatic [1]; some thyroid nodules may become so large that they put pressure on the trachea, causing breathing problems and difficulty swallowing [2]
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