Correlation between FEV1/FVC ratio with Body Mass Index (BMI) and absolute eosinophils in patients with acute exacerbation of asthma at Mataram City Hospital, West Nusa Tenggara in 2019–2020

Abstract

This study aimed to analyze Correlation between FEV1/FVC ratio with body mass index (BMI) and absolute eosinophils in patients with acute exacerbation of asthma. A cross sectional study based on the medical records of asthma patients from June 2019 to June 2020, with a total population of 180 cases conducted at Mataram City Regional General Hospital, West Nusa Tenggara. The data were analyzed using multiple linier regression using SPSS. The data collected showed that getting older reduces the value of FEV1/FVC, but it is not statistically significant (b= -0.03; 95% CI= -0.18 to 0.13; p= 0.746). Male gender has a lower probability of having a FEV1/FVC value than female sex, but it is not statistically significant (b= -2.78; 95% CI= -6.38 to 0.83; p= 0.130). An increase in the eosinophil score reduced the FEV1/FVC value by 6.03 units and was statistically significant (b= -6.03; 95% CI= -7.80 to -4.26; p< 0.001). An increase in body mass index decreased the FEV1/FVC value by 1.22 units and was statistically significant (b= -1.22; 95% CI= -1.71 to -0.75; p< 0.001).