CORRELATION BETWEEN EPITHELIAL DYSPLASIA AND ORAL SQUAMOUS PAPILLOMA AS A RESULT OF MULTIPLE RISK FACTORS: A CLINICAL CASE

Abstract

This study is a clinical case of a 64-year-old leukoderma female patient, smoker for more than 45 years, who, after being diagnosed with Hepatitis A and B in different periods, presented a single leukoplastic, verrucous, pedunculated nodule, of the "cauliflower" type, on the lower alveolar edge of the right side (lesion I). It also presented homogeneous leukoplastic plaque, with verrucous surface, in the region of the lateral border of the tongue on the left side (lesion II). Both lesions were asymptomatic, with an undefined onset. The probable diagnostic hypotheses were squamous papilloma (lesion I) and leukoplakia (lesion II), with a differential diagnosis of condyloma (lesion I) and lichen planus (lesion II). Biopsy was performed by excisional removal of lesion I and incisional removal of lesion II, with the diagnosis of oral squamous papilloma and moderate to severe oral epithelial dysplasia, respectively. There was no radiographic lesion. Patient is undergoing follow-up. This study is a clinical case of a 64-year-old leukoderma female patient, smoker for more than 45 years, who, after being diagnosed with Hepatitis A and B in different periods, presented a single leukoplastic, verrucous, pedunculated nodule, of the "cauliflower" type, on the lower alveolar edge of the right side (lesion I). It also presented homogeneous leukoplastic plaque, with verrucous surface, in the region of the lateral border of the tongue on the left side (lesion II). Both lesions were asymptomatic, with an undefined onset. The probable diagnostic hypotheses were squamous papilloma (lesion I) and leukoplakia (lesion II), with a differential diagnosis of condyloma (lesion I) and lichen planus (lesion II). Biopsy was performed by excisional removal of lesion I and incisional removal of lesion II, with the diagnosis of oral squamous papilloma and moderate to severe oral epithelial dysplasia, respectively. There was no radiographic lesion. Patient is undergoing follow-up.