Abstract
The correlation between the electrophoretic mobility of residual IgG in hypogammaglobulinaemic sera and the distribution of IgG sub-classes was studied. It was found that IgG from sera with raised levels of IgG2 show fast electrophoretic mobility, and sera with very low or absent IgG2 show a slow moving IgG. IgG3 was absent or just detectable in fast moving IgGs, and present in higher titers in some slow IgGs.
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