Abstract

Introduction: We investigated the association between echocardiographic left ventricular mass (LVM) indexed to body surface area (LVM/BSA) or height2.7 (LVM/H2.7) and electrocardiographic (ECG) variables in 546 Chinese hypertensives. Methods: Cornell voltage, Sokolow-Lyon voltage, maximum R amplitude in V1-V6, Gubner-Ungerleider voltage and the products with QRS duration of these amplitude variables were evaluated. Results: In our study, LVM/H2.7 was significantly related to body mass index, but not gender. Correlation between ECG variables and LVM/H2.7 was similar to that of LVM/BSA. In obese and overweight subgroups, Cornell product was the best predictor for both LVM/BSA and LVM/H2.7; the correlation trended to be stronger as LVM/BSA or LVM/H2.7 increased. Correlation coefficient between LVM/BSA and Cornell product was 0.529 for male obesity, 0.597 for female obesity, 0.451 for male overweight and 0.345 for female overweight patients. When LVM was indexed to height2.7, the r values were 0.559, 0.589, 0.427 and 0.360 respectively. Fewer ECG variables showed weak correlation with LVM/BSA in the hypertensives without left ventricular hypertrophy. Conclusions: We concluded that LVM/H2.7 might well predict LVM in Chinese hypertensives, and that Cornell product was the best parameter for the prediction of both LVM/BSA and LVM/H2.7 in obese and overweight hypertensives, whereas estimation of LVM/BSA by ECG was inaccurate in Chinese hypertensives without left ventricular hypertrophy.

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