Correlation between disease severity and quality of life index in psoriasis patients treated with Lactobacillus plantarum IS-10506

Abstract

Psoriasis is a chronic and relapsing inflammatory skin disease that affects both genders at all ages. The purpose of this study is to identify the correlation between psoriasis area severity index (PASI) and Dermatology Life Quality Index (DLQI) for patients with plaque psoriasis before and after treatment with Lactobacillus plantarum IS-10506. This was a before after cohort study. Adults with mild to moderate psoriasis were recruited into the study. All participants received the original Indonesian probiotic strain Lactobacillus plantarum IS-10506 at a dose of 2x1010 colony forming units (CFU) per day for six weeks. A total of 22 patients, with a mean age of 43 years, participated in the study. Participants had psoriasis for an average of 14 years. There was a correlation between PASI score and several quality-of-life questionnaire elements in certain condition, such as professional jobs, unemployment, obesity, and joint symptoms. The correlation between particular conditions reveals that occupations, obesity, and joint symptoms have a greater impact on psoriasis patients.