Correlation between Degree of HT with Degree of Albuminuria in Non-dialysis Chronic Kidney Disease Patients at Hypertension Kidney Polyclinic Dr. Soetomo General Hospital

Abstract

Background: Hypertension (HT) in chronic kidney disease (CKD) occurs through increased activity Renin Angiotensin Aldosterone System (RAAS). According ISH 2020, degree of HT is divided into grade 1 and 2. Uncontrolled HT cause damage glomerular capillaries, thereby affecting presence of albuminuria. According KDIGO 2013, degree of albuminuria is divided into mild, moderate, and severe. Albuminuria that lasts more than 3 months indicates CKD. Until now, research on correlation between degree of HT with degree of albuminuria is still limited. This study aims to determine correlation between degree of HT with degree of albuminuria in non-dialysis CKD patients at Hypertension Kidney Polyclinic Dr. Soetomo General Hospital. Methods: Analytical observational study with cross sectional design using medical records of non-dialysis CKD patients at Hypertension Kidney Polyclinic Dr. Soetomo General Hospital for period of May-October 2021, according to inclusion and exclusion criteria. Correlation test using spearman test. Results: There were 75 study subjects with male (61.3%), age 46-65 years old (42.7%), comorbidities other than HT were DM (32%), HT duration <5 years (58.7% ), controlled HT (66.7%), taking 1 anti-HT (74.7%), ARB (26.7%), severe albuminuria (50.7%). This study showed no correlation between degree of HT with degree of albuminuria (p-value=0.982). Conclusion: There is no correlation between degree of HT with degree of albuminuria in non-dialysis CKD patients at Hypertension Kidney Polyclinic Dr. Soetomo General Hospital.