Correlation between COPD duration and abnormality in FEV1, FVC, and BODE index in 100 COPD patients

Abstract

Background: Progression of any disease depends on several factors and one such factor is duration. To determine the progression of chronic obstructive pulmonary disease (COPD), post-bronchodilator forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and BMI, Obstruction, Dyspnea, Exercise (BODE) index are considered. We have tried to find a correlation between these factors and the duration of disease; to check how these factors fare as the disease progresses. Aims and Objectives: The aim of the study was to correlate COPD duration with post bronchodilator FEV1, FVC, and BODE index, respectively. Materials and Methods: A hospital-based and cross-sectional study was conducted at department of respiratory medicine, GCS Medical College, Hospital, and Research Centre, Ahmedabad, Gujarat among COPD patients. Informed consent was obtained from each patient. We analyzed 100 patients of COPD diagnosed by symptoms, presence of risk factors, and spirometry. Detailed clinical history, physical examination, and necessary investigations were conducted in all patients. Results: Out of which 71 were newly diagnosed cases while 29 were known cases of COPD. On correlating COPD duration with post-bronchodilator FEV1, FVC, and BODE index; we did not find any correlation between them. Conclusion: We would like to recommend a similar study with a larger population size to arrive at some form of conclusion.