Correlation between continued end-tidal carbon dioxide tension and invasive arterial blood pressure during cardiopulmonary resuscitation in children of pediatric intensive care unit

Abstract

Objective To explore the changes of end-tidal carbon dioxide tension (PETCO2) and continued invasive arterial blood pressure during cardiopulmonary resuscitation (CPR) in children of pediatric intensive care unit (PICU) and the correlation between them. Methods A total of 63 pediatric patients with CPR of PICU in Zhengzhou Children's Hospital from January 2016 to January 2017 were included. The pediatric patients were divided into successful group (n=49) and losing group (n=14) according to the results of CPR. This study analyzed the changes of PETCO2 and invasive arterial blood pressure during CPR in children of pediatric patients in two groups 0 min, 5 min, 10 min, 20 min, 30 min, 1 h, 3 h, 12 h, 24 h during CPR and explored the correlation between them. The study used SPSS 17.0 software for data analysis. Results The PETCO2, invasive systolic pressure, invasive diastolic pressure and mean invasive arterial blood pressure of pediatric patients in successful group all raised and remained stable 30 min after CPR. Otherwise, those values of pediatric patients in losing group during CPR raised momently and droped rapidly, and then could not be measured after 30 min. The PETCO2 pediatric patients in successful group 5 min, 10 min, 20 min and 30 min during CPR was higher than that in losing group with significant differences (P<0.05) . The invasive systolic pressure, invasive diastolic pressure and mean invasive arterial blood pressure of pediatric patients 20 min and 30 min during CPR in successful group were all higher than those in losing group with significant differences (P<0.05) . The PETCO2 was positively associated with the mean invasive arterial blood pressure (P<0.05) . Conclusions The PETCO2 and invasive arterial blood pressure can be the predictors of CPR outcomes from pediatric patients and provide a basis for successful rescues. They are worth to be used widely in pediatric CPR. Key words: Cardiopulmonary resuscitation; Pediatric intensive care unit; End-tidal carbon dioxide tension; Invasive arterial blood pressure; Correlation