Correlation between clinical diagnoses with qualitative levels of serum methanol and correlation between indirect laboratory examination with quantitative levels of serum methanol in methanol intoxication patients

C Rintawan,H.A Rasyid,A Haedar,A Prasetyadjati

doi:10.18551/biotika.2018-05.02

Abstract

Correlation between clinical diagnoses with qualitative levels of serum methanol and correlation between indirect laboratory examination with quantitative levels of serum methanol in methanol intoxication patients

Highlights

Around the world, cases of methanol intoxication are still common, especially in countries that prohibit the sale of alcohol freely
Data is recorded in a special registry which is collected and analyzed using normality test to determine the distribution of data and continued with Spearman correlation test to test the correlation between indirect laboratory results and Methanol levels
Based on the results and discussion of the research described above before, there are some conclusions that can be drawn from this study namely; there is no correlation between clinical diagnosis and qualitative levels of serum methanol

Summary

Introduction

Cases of methanol intoxication are still common, especially in countries that prohibit the sale of alcohol freely. This study aims to determine correlation between clinical diagnosis with qualitative levels of serum Methanol and correlation between indirect laboratory examination (pH, anion gap, lactate and blood osmolality) with quantitative levels of serum methanol in methanol intoxication patients. Enforcement of a diagnosis of methanol poisoning is done by checking serum methanol levels in the patient's blood This examination is often not available in most ED so that other laboratory tests are needed that can support the diagnosis and are more available in hospitals (WHO, 2014). This study analyzed the relationship between indirect laboratory tests (pH, anion gap, osmolality and lactate) with serum methanol levels and the relationship of clinical diagnosis with direct laboratory examination (serum methanol quality test). From this study it is hoped that it can help the clinicians in diagnosing patients with suspected methanol poisoning

Objectives

Methods

Findings

Conclusion