Abstract

To explore the correlation between body composition measurement by bioelectrical impedance analysis (BIA) and intradialytic hypotension (IDH). The clinical data of 127 patients with end-stage renal disease (ESRD) who underwent regular dialysis in the Blood Purification Center of the Second Affiliated Hospital of Chongqing Medical University were retrospectively analyzed. According to the occurrence of IDH, the patients were divided into IDH group and intradialytic normotension group. The difference in body composition measured by BIA and its relationship with IDH were compared between the two groups. Compared with intradialytic normotension group, the intracellular water (ICW) ratio (P = 0.009), extracellular water (ECW) ratio (P = 0.029), total body water (TBW) ratio (P = 0.012), protein ratio (P = 0.010), soft lean mass (SLM) ratio (P = 0.011), fat-free mass (FFM) ratio (P = 0.012) and skeletal muscle mass (SMM) ratio (P = 0.009) in IDH group were significantly decreased. However, the fat mass (FM) ratio (P = 0.016), percentage body fat (PBF) ratio (P = 0.001), extracellular water/total body water (ECW/TBW) ratio (P = 0.036), extracellular water/total body water in trunk (ECW/TBWT) ratio (P = 0.045) and visceral fat area (VFA) (P = 0.003) in IDH group were significantly increased when compared with intradialytic normotension group. In addition, there was a positive correlation between systolic blood pressure (SBP) during IDH and ECW ratio, ECW/TBW ratio, and ECW/TBWTR ratio before dialysis. The body composition of dialysis patients is closely related to the occurrence of IDH. Strengthening the body composition management of dialysis patients outside the hospital may reduce the occurrence of IDH and improve the long-term prognosis of dialysis patients.

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