Abstract
PSA is a glycoprotein, which is present in both normal and pathological prostatic tissue, so it can be detected in the serum of patients with a normal prostate, BPH or prostatic cancer (PC). BPH and PC have the highest clinical incidence in the same agevange. The exact role of hypertrophic tissue in the variations of PSA serum levels must be determined when utilizing it as a tumoral marker of prostatic cancer. In order to determine it we matched serum PSA levels and prostate weight in 61 patients with BPH, proved by histological examination. Only in one case the value was higher than 20 ng/ml. So, in our opinion this value is the cut off. If the adenoma weight is 25–30 g or more, rectal examination and echography are normal, a biopsy is mandatory.
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