Correlation between Absolute Neutrophil Count Level and Helicobacter Pylori Infection in Pediatric Gastritis

Abstract

Helicobacter pylori infection is the most common cause of gastritis worldwide and associated with gastric ulcer and cancer. There are not many studies assessing the significance of baseline and clinical characteristics, and absolute neutrophil count (ANC) in H. pylori associated gastritis. Objective: Assessing the correlation of baseline and clinical characteristics and ANC with pediatric H. pylori associated gastritis. Method: This was an analytical cross sectional research to pediatric patients with gastritis in Haji Adam Malik and Universitas Sumatera Utara hospitals between October ? December 2020. H. pylori screening and ANC test were conducted. Independent t-test and Mann-Whitney test were used to assess the correlation. Result: From 82 research subjects, 45 subjects were positive H. pylori and 37 subjects were negative. Demographic data, such as age, gender, ethnicity, socioeconomic status, level of education of children and parents, and parents? occupation, was not significantly correlated to H. pylori infection. Clinical data, such as body height and weight, nutritional status, and symptoms, was not significantly correlated to H. pylori infection. There was no significant difference between ANC and H. pylori infection in the two groups. Conclusion: There were no significant differences in baseline and clinical characteristic data and ANC with pediatric H. pylori gastritis.