Correlation analysis of upper extremity lymphedema and axillary lymph node positive rate after modified radical mastectomy for breast cancer

Abstract

Objective To investigate the correlation between upper limb lymphedema and axillary lymph node positive rate after modified radical mastectomy. Methods A retrospective study was performed on 112 patients with breast cancer who underwent modified radical mastectomy from November 2014 to November 2016. The patient’s upper limb lymphedema was measured according to the circumferential diameter measurement method, and the patients without edema appeared as the control group. Patients with edema were included in the edema group, and SPSS18.0 was used for analysis. Logistic single factor and multivariate analysis were performed on the positive rate of upper limb lymphedema and axillary lymph nodes in the two groups. The symptoms of upper limb lymphedema in the two groups were compared with χ2. P<0.05 difference was statistically significant. Results The results of single factor analysis showed that there were correlations between body mass index, lymph node metastasis, postoperative complications, tumor size, radiotherapy and upper limb lymphedema, and axillary lymph node positive rate (P<0.05). Multi-factor analysis of upper limb lymphedema showed that the independent risk factors were: body mass index, age, radiation therapy. (P<0.05). By contrast, the incidence of upper limb swelling and heavy feeling in the edema group was significantly higher than that in the control group (P<0.05). Conclusion There are many independent risk factors for upper limb lymphedema in patients with breast cancer. The risk factors should be highly valued. The relevant programs should be developed for treatment and corresponding measures should be taken to reduce the incidence of upper limb lymphedema. Key words: Breast neoplasms; Mastectomy, modified radical; Lymphedema