Correlation analysis of subjective sleep quality and mental resilience in colorectal cancer patients during the chemotherapy treatment period

Abstract

Objective To explore the subjective sleep quality and mental resilience in colorectal cancer patients during the treatment period. Methods A total of 72 colorectal cancer patients undergoing chemotherapy from May to September 2016 in First Affiliated Hospital of Xi'an Jiaotong University were selected by convenience sampling method. Pittsburgh sleep quality index (PSQI) and Conner-Davidson Resilience Scale (CD-RISC) were applied to investigate patients' sleep quality and mental resilience before discharge, and at the 1st month, 3rd month and 6th month of the chemotherapy. Single factor repeated measurement analysis of variance was applied to compare the difference between sleep quality score and mental resilience score, and Pearson correlation coefficient was used to analyze the correlation between them. Results The PSQI scores at the 4 follow-up time points were (9.43±4.26) , (9.02±3.68) , (7.58±4.01) and (6.16±3.22) , and the difference was statistically significant (F=9.861, P<0.05) . The CD-RISC scores at the 4 follow-up time points were (60.13±15.80) , (66.56±16.17) , (69.82±17.46) and (73.03±17.85) , and the difference was statistically significant (F=7.681, P<0.05) . The difference of PSQI scores of patients in different age groups was statistically significant (F=2.792, P<0.05) , and the differences of CD-RISC in patients with different education degree and in different cancer stages were statistically significant (F=3.321, 3.534; P<0.05) . There were a negative correlations between sleep quality and mental resilience at the each time point (r=-0.32--0.53; P<0.05) . The CD-RISC score of the patients with early stage sleep disturbances was lower than that of non-sleep disturbances patients at each time point (P<0.05) . Conclusions Health professionals should pay close attention to the sleep status of colorectal cancer patients at the early stage of treatment, and take appropriate interventions to improve the quality of life and resilience development. Key words: Colorectal neoplasms; Questionnaires; Chemotherapy; Sleep disorders; Resilience, psychological