Correlating Hemodynamic Changes and Occlusion Time after Flow Diverter Treatment of Bilateral Large Internal Carotid Artery Aneurysms.

Abstract

A middle-aged lady in good health presented right abducens nerve palsy. Magnetic resonance imaging (MRI) of the brain showed bilateral cavernous ICA aneurysms. The left aneurysm measured 9 × 7 mm whereas the right aneurysm measured 22 × 15 mm, with mass effect on the cavernous sinus, explaining her symptoms (Fig. 1). Both were wide-neck aneurysms and were treated with PED alone sequentially, 3 months apart. She was loaded with Aspirin 300 mg and Clopidogrel 300 mg before treatment, with Aspirin continuing for 6 months and Clopidogrel for 3 months afterwards. There were no procedural complications. Digital subtraction angiogram at 1 year showed that the left aneurysm was completely occluded, whereas the right aneurysm had partially thrombosed but with a persistent filling. The right aneurysm persisted on CT angiogram at 2 years but with significant shrinkage and finally occluded at a 3-year follow-up (Fig. 2). The patient’s diplopia gradually improved after 3 years.