Abstract
Introduction: The research emphasises on the association bond of correlation of biochemical radiological and cytological outcomes of pleural effusion
 Material and Methods: The samples for the study were collected from the diagnostic centre, out-patient department and in-patient department of Department of Biochemistry, Internal Medicine, Respiratory Medicine at Rabindranath Tagore Medical College, Udaipur, Rajasthan The research was carried out on a total of 100 patients .The observations took about a year’s time. The research was carried out on a total of 100 patients,
 Results: 100 patients with pleural effusion were studied of which 60.00% were cases of tuberculous effusion and 40.00% were cases of non tuberculous effusion. This was reflective of the high prevalence of tuberculosis in the area being studied. The remaining 40 cases were of malignant effusion (15 cases), Transudative effusion (13 cases), synpneumonic effusion (8 cases) and 4 cases of empyema.. In patients of age more than 40 years, malignant effusion was more common; It was found more common in lower socioeconomic class such people live in crowded, unhygienic conditions. The commonest symptoms were cough (81.32%) and breathlessness (78.76%), followed by fever 69.20%, weight loss 64.64%, chest pain 45.50%, loss of appetite 63.30% and hemoptysis 15.80%.
 Conclusion: Thus it can be concluded that ADA is elevated in tubercular pleural effusion. Exudatives had decreased glucose but increased protein, LDH and cholesterol compared to transudatives Pleural fluid cytology revealed elevated Lymphocytes in tubercular and polymorphs in acute infections
 Keywords: Lactate dehydrogenase, Adenosine Deaminase biochemical, radiological and cytological outcomes of pleural effusion
Highlights
IntroductionPleural effusion refers to the excessive or abnormal accumulation of fluid in the pleural space
The research emphasises on the association bond of correlation of biochemical radiological and cytological outcomes of pleural effusion Material and Methods: The samples for the study were collected from the diagnostic centre, out-patient department and in-patient department of Department of Biochemistry, Internal Medicine, Respiratory Medicine at Rabindranath Tagore Medical College, Udaipur, Rajasthan The research was carried out on a total of 100 patients .The observations took about a year’s time
Exudatives had decreased glucose but increased protein, LDH and cholesterol compared to transudatives
Summary
Pleural effusion refers to the excessive or abnormal accumulation of fluid in the pleural space. Pleural effusion presents a diagnostic dilemma, as no cause may be found in about 19% of cases, in spite of careful evaluation[2]. India has the highest prevalence of tuberculosis in the world with 2/3rds of all TB patients being in India[3]. Tuberculosis is the most common cause of effusion in India when compared to the West where malignancy and parapneumonic effusions are more common[4]. Pleural tuberculosis is second in frequency after TB lymphadenitis. The clinical, biochemical and cytological parameters of tubercular effusion are shared by malignancy, both being exudates and predominantly lymphocytic effusions. There is a need for defining the best and on-time diagnostic approach to diagnose transudative and exudative pleural effusion quickly. Dr Shuchi Goyal et al, International Journal of Medical and Biomedical Studies (IJMBS)
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