Abstract

British Journal of PharmacologyVolume 178, Issue 12 p. 2548-2548 CORRECTIONFree Access Correction This article corrects the following: Betulinic acid inhibits endotoxin-stimulated phosphorylation cascade and pro-inflammatory prostaglandin E2 production in human peripheral blood mononuclear cells Vijayan Viji, Antony Helen, Varma R Luxmi, Volume 162Issue 6British Journal of Pharmacology pages: 1291-1303 First Published online: February 22, 2011 First published: 24 May 2021 https://doi.org/10.1111/bph.15519AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL The authors of Vijayan et al. (2011) have supplied the following correction to their article. Author mistakes during manuscript preparation resulted in errors in the images presented in Figure 4a, ERK1/2 (panel 3), and Figure 4b. For Figure 5, beta-actin was erroneously shown as part of the analysis which it was not and this has now been removed. The corrected figures are provided below. FIGURE 4Open in figure viewerPowerPoint BA inhibits LPS-induced phosphorylation of extracellular regulated kinase (ERK) 1/2 (A) and Akt (C) but not p38 (B) in hPBMCs. hPBMCs were pretreated with BA (1–2 μg.ml−1) for 30 min. LPS (1 μg.ml−1) was then added and incubated for 30 min. Cell lysates were subjected to Western blotting with their relevant antibodies against COX-2, Akt, 3phospho-ERK and phospho-p38. Membranes were cut and probed with different antibodies. To assess non-phosphorylated forms of ERK, p38, the membranes were stripped and reprobed with specific antibodies. Photographs of chemiluminescent detection of the blots, which were representative of three independent experiments, are shown. The relative abundance of each band to its own β-actin was quantified. Data are presented as mean SEM; n = 6. #Significantly different from basal values (P < .05). *Significantly different from LPS control (P < .05). BA, betulinic acid; hPBMCs, human peripheral blood mononuclear cells; LPS, lipopolysaccharide FIGURE 5Open in figure viewerPowerPoint The quantification as shown in Figures 2 and 4 in the article remain unchanged and the authors state that these mistakes do not affect the results or conclusions of this study. The authors sincerely apologize for these mistakes. The authors would also like to update the email address of the Corresponding Author to [email protected]. REFERENCE Viji, V., Helen, A., & Luxmi, V. R. (2011). Betulinic acid inhibits endotoxin-stimulated phosphorylation cascade and pro-inflammatory prostaglandin E2 production in human peripheral blood mononuclear cells. British Journal of Pharmacology, 162, 1291– 1303. https://doi.org/10.1111/j.1476-5381.2010.01112.x Volume178, Issue12June 2021Pages 2548-2548 FiguresReferencesRelatedInformation

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