Abstract
HomeCirculation ResearchVol. 97, No. 1Correction Free AccessCorrectionPDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessCorrectionPDF/EPUBCorrection Originally published3 Apr 2018https://doi.org/10.1161/res.97.1.e6Circulation Research. 2005;97:e6This article corrects the followingHMG-CoA Reductase Inhibitors Inhibit Endothelial Exocytosis and Decrease Myocardial Infarct SizeIn an article published by Yamakuchi et al (Circ Res. 2005:96:1185–1192.), Figure 5 contained an errors in Panel B. The corrected figure is below: Download figureDownload PowerPointFigure 5. Simvastatin inhibited leukocyte rolling in vivo. A, Simvastatin decreased leukocyte adhesion to murine venules. Mice were treated with vehicle (PBS) or simvastatin (1 mg/kg) IP, and after 24 hours the mice were anesthetized and injected with rhodamine 6G to label leukocytes. The mesentery was exteriorized, superfused with 20 μL histamine 1 mmol/L, and rolling leukocytes were imaged with a fluorescent digital camera. B, Quantification of simvastatin inhibition of leukocyte adhesion in mice (n=3 to 5±SEM. *P<0.04 vs vehicle). C, Simvastatin increased S-nitrosylation of NSF in vivo. Wild-type or eNOS knockout mice were treated with simvastatin for 24 hours, and spleen lysates were immunoprecipitated with antibody to nitrosocysteine. Precipitants were fractionated and immunoblotted with antibody to NSF (upper) to detect nitrosylated NSF (NSF-NO). To confirm that simvastatin did not change total NSF expression, total cell lysates were also immunoblotted with antibody to NSF (lower). Previous Back to top Next FiguresReferencesRelatedDetailsRelated articlesHMG-CoA Reductase Inhibitors Inhibit Endothelial Exocytosis and Decrease Myocardial Infarct SizeMunekazu Yamakuchi, et al. Circulation Research. 2005;96:1185-1192 July 8, 2005Vol 97, Issue 1 Advertisement Article InformationMetrics https://doi.org/10.1161/res.97.1.e6 Originally publishedApril 3, 2018 PDF download Advertisement
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