Abstract
Correction: Quantification of Hepatic Iron Concentration in Chronic Viral Hepatitis: Usefulness of T2-weighted Single-Shot Spin-Echo Echo-Planar MR Imaging
Highlights
Abnormalities of iron metabolism are frequently observed in patients with chronic liver diseases such as viral hepatitis, nonalcoholic fatty liver disease, and cirrhosis [1,2]
Kato et al [10] stated that phlebotomy therapy may potentially lower the risk of progression to hepatocellular carcinoma (HCC) in patients with hepatitis C virus infection
We reviewed the patients who admitted use of both liver specimens and MR images before hepatic surgery at our institution between January 2007 and April 2008 and identified patients who met the following inclusion criteria: (a) patients had both chronic viral hepatitis/cirrhosis and HCC; (b) patients underwent abdominal MR imaging with T2-weighted gradient-recalled echo (GRE) sequence and DW-EPI sequence with b-factors of 0 s/mm2, 500 s/mm2, and 1000 s/mm2; and (c) patients underwent an operation for HCC and received a histopathologic diagnosis of either chronic hepatitis or cirrhosis that was based on findings at surgical resection, performed within a month after MR imaging
Summary
Abnormalities of iron metabolism are frequently observed in patients with chronic liver diseases such as viral hepatitis, nonalcoholic fatty liver disease, and cirrhosis [1,2]. Several research groups have reported on the efficacy of iron reduction therapies by phlebotomy [4,5,6,7,8,9,10]. Yano et al [6] reported that phlebotomy therapy contributed to improvement of biochemical markers in patients with hepatitis C virus infection. Kato et al [10] stated that phlebotomy therapy may potentially lower the risk of progression to hepatocellular carcinoma (HCC) in patients with hepatitis C virus infection. Precise quantification of hepatic iron overload might be beneficial for managing iron reduction therapy in patients with chronic viral hepatitis
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