Abstract

Correction: Post-Operative Recurrent Trachomatous Trichiasis Is Associated with Increased Conjunctival Expression of S100A7 (Psoriasin)

Highlights

  • Trachoma remains the leading infectious cause of blindness worldwide [1]

  • As there was no difference in the trachomatous trichiasis (TT) recurrence rate between the two alternative sutures, subjects for this nested case-control study were drawn from both trial arms and data combined [12]

  • Comparing the eligible and excluded people: there was no difference in the proportion who were female (p = 0.3), the eligible group was slightly younger (49 years vs. 51 years, t-test p = 0.02) and had slightly more severe baseline trichiasis

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Summary

Introduction

Trachomatous Trichiasis (TT) is the potentially blinding stage of this disease in which the eyelashes scratch the surface of the globe, resulting in corneal opacification [2,3,4]. It is the result of a progressive scarring process of the tarsal conjunctiva, which is initiated in childhood by recurrent episodes of Chlamydia trachomatis infection that are characterised by inflammation. Recurrence, which may be defined as that developing within the first six months following surgery, appears to occur with a greater incidence rate than late recurrence [9]. Recurrent TT following surgery is common, probably due to various surgical and disease factors. In this study we investigated the relationship between recurrent trichiasis and the expression of various cytokines and fibrogenic genes during a two-year follow-up period

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