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Abstract
Critically ill patients admitted to intensive care units for the clinical manifestations of stress hyperglycemia represent a group in which attempts are most frequently undertaken to employ various methods of its correction. Objective: to compare different techniques for correction of stress hyperglycemia in patients with acute surgical abdominal disease complicated by peritonitis. Materials and methods: In this single-center randomized controlled trial, stress hyperglycemia was corrected by different procedures in 60 patients with acute surgical abdominal disease complicated by peritonitis. Results: As compared with traditional procedures for correction of stress hyperglycemia, the human insulin analogue aspart (Novorapid) improves stressful glycemic control and reduces the risk of hypoglycemia. During intensive insulin therapy, the ultrashort-acting insulin group showed showed a trend for a reduction in the number of manifestations of multiple organ failure and signs of systemic inflammation and decline in the number of hospital days. The least duration of mechanical ventilation was noted in the small-volume food group.
Highlights
Пациенты отделений реанимации и интенсивной терапии, находящиеся в критическом состоянии и имеющие клини ческие проявления стрессовой гипергликемии, являются той группой больных, где наиболее часто предпринимаютcя попытки использовать различные методы ее коррекции
Ill patients admitted to intensive care units for the clinical manifestations of stress hyperglycemia represent a group in which attempts are most frequently undertaken to employ various methods of its correction
Objective: to compare different techniques for correction of stress hyperglycemia in patients with acute surgical abdominal disease complicated by peritonitis
Summary
Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal Diseases. Цель: сравнение различных методик коррекции стрессовой гипергликемии у больных с острой хирургической патологией органов брюшной полости, осложненной перитонитом. В одноцентровом рандомизированном контролируемом исследовании проведена коррекция стрессовой гипергликемии у 60 больных с острой хирургической патологией органов брюшной полости, осложненной перитонитом, разделенных на две группы, с использованием различных методик коррекции. Objective: to compare different techniques for correction of stress hyperglycemia in patients with acute surgical abdominal disease complicated by peritonitis. Алгоритм проведения интенсивной инсулинотера пии (ИИТ) разработан еще в прошлом веке и заключа ется в проведении непрерывной инфузии инсулина короткого действия с такой скоростью, которая необ ходима для достижения нормогликемии [9]. Цель исследования — сравнение различных мето дик коррекции стрессовой гипергликемии у больных с острой хирургической патологией органов брюшной полости (ОХПОБП), осложненной перитонитом
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