Correction of involutional skin changes using microfocused ultrasound combined with PRP-therapy

Abstract

Introduction:In aesthetic medicine, the use of hardware technologies occupies an important place. Hardware action on skin includes microfocused ultrasound, radiowave, light and laser methods. The ultimate task of each method consists in improving the condition of skin and its rejuvenation. However, to enhance the clinical efficiency, combined actions have been suggested recently.Objective:To compare the effect of microfocused ultrasound as monotherapy and the combined application thereof with autologous blood cell factors.Methods:For assessing efficiency of the procedures undertaken, the data of ultrasonic scanning of skin were studied, photo documentation was performed, and adapted dermatological indices were used: the dermatological status index (DLQI) and WAM index (wellbeing, activity, mood).Results:According to the research results, ultrasonic skin scanning data were obtained which gave evidence about a more pronounced clinical effect in patients having received the combined application of microfocused ultrasound with autologous blood cell factors. The improvement of qualitative characteristics of skin in the form of a thicker dermal stratum and improved dermal coefficient was observed both in the patients having received monotherapy by microfocused ultrasound and in the group where patients underwent its combined application with autologous blood cell factors. However, the improvement of clinical effect was significantly higher in patients having received the combined application as compared to the microfocused ultrasound monotherapy group, which confirms the synergism of the hardware method and the use of factors of autologous blood cells (thrombocytes). Such manifestations as a significant increase of thickness of epidermis in 6 months in patients having received the microfocused ultrasound monotherapy gives an indirect evidence about the presence of compensated dehydration in reparative processes; this is a norm, but it curbs performance of other stimulations. Photo documentation and the analysis of dermatological indices also correlated with the data of US examination of skin. The pronounced clinical efficiency in the use of combined treatment confirms the synergism of the said two methods aimed at improving the quality of skin.Conclusion:The use of autologous blood cell factors significantly improves clinical results and allows employing other stimulation procedures in the integrated correction (laser technologies, radiofrequency methods) after microfocused ultrasound within the periods of up to 6 months after treatment.