Abstract

Nowadays cancer chemotherapy includes antibiotics, antimetabolites, alkylates, topoisomerase inhibitors and mitotic inhibitors, hormones. The search for medicinal plants that can prophylactically prevent or at least slow down the homeostasis disturbance is especially relevant. To date, the most widely used for the body restoring plant is licorice. By reducing the oxidative stress, licorice components contribute to the restoration of vitality of non-cancer cells. With a multifaceted effect on receptormediated signaling, pro- and anti-inflammatory processes, licorice compounds are drugs of choice to eliminate adverse reactions after cancer chemotherapy. This herb has long been used in the East as an adjuvant for adverse reactions. In this article, we discuss the main mechanism of anticancer drugs action along with the protective properties of licorice. Conclusion: Licorice reduces the symptoms of mucositis, anorexia, chronic fatigue during cancer treatment, has a hepatoprotective effect, helps to restore the immune cells activity

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