Abstract

The use of the terms and and in the article can be misleading and should therefore be replaced by the two compounds' formal name and Cas-number. Texanol A should be replaced by Propanoic acid,2-methyl-, 1-(2-hydroxy-1-methylethyl)-2,2-dimethylpropyl ester (Cas-number 74367-33-2) and Texanol B should be replaced by Propanoic acid,2-methyl-, 3-hydroxy-2,4,4-trimethylpentyl ester (Cas-number 74367-34-3).

Highlights

  • Global trend in prevalence of allergic airway disease and other types of allergies in children and young adults appears to be stabilizing or even decreasing since the 1990s in ‘‘western’’ countries [1]

  • We propose a novel hypothesis that propylene glycol and glycol ethers (PGEs) in indoor air exacerbate and/or induce the multiple allergic symptoms, asthma, rhinitis and eczema, as well as IgE sensitization respectively

  • In order to examine complex volatile organic compounds (VOCs) mixture at low concentration range, we examined the risks of eight classes of VOCs, defined in terms of their chemical properties

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Summary

Introduction

Global trend in prevalence of allergic airway disease and other types of allergies in children and young adults appears to be stabilizing or even decreasing since the 1990s in ‘‘western’’ countries [1]. A substantial portion of the population, especially the children, suffers from these diseases which make it a public health concern. Causal factors underlying these diseases and other contributors of global trend in prevalence since the 1970s remain unknown [2]. The risk of indoor exposure to volatile organic compounds (VOCs) on allergic airway diseases in children remains unknown

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