Corrected sinus node recovery time indices to predict atrial fibrillation recurrences post pulmonary vein isolation in persistent atrial fibrillation patients

Abstract

Objective: To evaluate the corrected sinus node recovery time(CSNRT) in relation to atrial fibrillation(AF) recurrences post pulmonary vein isolation in persistent atrial fibrillation patients. Methods: A total of 30 patients with persistent AF admitted to Lu’an group general hospital and underwent catheter ablation (CPVA+CFAE+LA Linear ablation, CCL) from October 2012 to October 2015 were enrolled in this study. These patients were divided into two groups, i.e. recurrence group and non-recurrence group during the follow up period. Multivariate Logistic regression was used for analysis of recurrent prediction in patients after Radiofrequency catheter ablation (RFCA) therapy. Results: No significant difference was shown with respect to sex, age, AF history, pathologic heart disease, hypertension, AF type, left ventricular end-diastolic diameter (LVEDD) intraoperative electrical cardioversion between the two groups (P>0.05). Left atrial diameter, CSNRT and early recurrence were shown a difference between the two groups (P<0.05). The results of logistic regression analysis showed that CSNRT (OR=4.457, 95%CI: 1.231-12.245, P<0.05) was an independent predictor for AF recurrence. Conclusions: The CSNRT consumes less time, as is favorable in lowering AF recurrence in patients after RFCA. Thus, the CSRNT can serve as an independent predictor for AF recurrence while the Sinus node function can be improved to ameliorate AF recurrence in patients after RFCA. Key words: CSNRT; Persistent atrial fibrillation; Radiofrequency ablation; Recurrence of atrial fibrillation