Abstract
We describe the case of a 71-years-old male, who was submitted to a left laparoscopic radical nephrectomy for Clear Renal Cell Carcinoma (CRCC). After a 14-year follow-up, MRI scan showed a 5-cm solid lesion of the perineum, that originates from the right corpus cavernosum. A percutaneous trans-perineal biopsy revealed an atypical metastasis of CRCC. To reduce surgical risk during the exeresis of the mass, the patient received 4 cycles of pazopanib as presurgical treatment, with a shrinking of the lesion at follow-up MRI scan. He underwent a complete resection of the residual mass. Histopathology confirmed the diagnosis of atypical corpus cavernosum metastasis of CRCC. Presurgical therapy with Target Molecular Therapy (TMT) is feasible and might have several potential advantages for patients in case of complex metastasectomy.
Highlights
Up to 30% of Renal-Cell Carcinoma (RCC) patients are metastatic at diagnosis or metastases may be discovered during follow-up [1,2,3]
We describe the case of a 71-years-old male, who was submitted to a left laparoscopic radical nephrectomy for Clear Renal Cell Carcinoma (CRCC)
Synchronous or metachronous RCC metastases typically occur to the brain, lungs, bones, liver, adrenals; atypical location appears to be rare and may involve numerous distant sites [4]
Summary
Corpus Cavernosum Atypical Metastasis of Renal Cell Carcinoma: Presurgical Therapy and Complete Surgical Resection. Case Report and Review of the Literature. Saccà A1#*, Roscigno M1#, Nicolai M1, Manica M1, La Croce G1, Bettini A2, Chirco A2, Bonomi L2 and Da Pozzo L2
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