Abstract
Quantitative MRI measurements of the sagittal surface area of the corpus callosum (CC) in 72 preterm individuals tested at adolescence (14-15 years) were compared with verbal skills on neuropsychological tests in a study at the Institute of Psychiatry, De Crespigny Park, London, UK.
Highlights
Quantitative MRI measurements of the sagittal surface area of the corpus callosum (CC) in 72 preterm individuals tested at adolescence (14-15 years) were compared with verbal skills on neuropsychological tests in a study at the Institute of Psychiatry, De Crespigny Park, London, UK
In preterm individuals who had a periventricular hemorrhage in the neonatal period, the decrease in CC area was greater
Verbal IQ and verbal fluency scores were lower in male adolescents with reduced total mid-sagittal CC size and mid-posterior surface area
Summary
Quantitative MRI measurements of the sagittal surface area of the corpus callosum (CC) in 72 preterm individuals tested at adolescence (14-15 years) were compared with verbal skills on neuropsychological tests in a study at the Institute of Psychiatry, De Crespigny Park, London, UK. Total CC area in very preterm adolescents was 7.5% smaller than in controls (p=0.015). In preterm individuals who had a periventricular hemorrhage in the neonatal period, the decrease in CC area was greater. Verbal IQ and verbal fluency scores were lower in male adolescents with reduced total mid-sagittal CC size and mid-posterior surface area.
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