Abstract
‘The knowledge contained in the book demonstrates how quickly and relatively efficiently the worldwide research community can meld together into a giant collaborative effort and concentrate its resources to rapidly begin to understand and solve problems, in this case a health problem.’ Coronaviruses cause respiratory and gastrointestinal diseases in various vertebrates, including minor respiratory diseases in humans. Because of that fact, focused research on these viruses was limited to a few dedicated, but talented, research groups. However, that changed in 2003, when a new coronavirus emerged, designated as severe acute respiratory syndrome corona-like virus (SARS-CoV), which caused a life-threatening respiratory disease characterized as an acute respiratory distress syndrome with a fatality rate of almost 10%. Suddenly, the world’s researchers devoted countless hours to attempting to identify, characterize and develop
Highlights
Some 4 years after the outbreak of SARS, this book edited by Volker Thiel tries to summarize the most recent advances in coronavirus molecular biology, vaccine development and coronavirus therapeutics, with great emphasis on SARS-CoV
The second part of the book consists of chapters that review the pathogenesis of coronavirus diseases, such as those caused by SARS-CoV, feline infectious peritonitis virus (FIPV), mouse hepatitis virus (MHV) and human NL63 coronavirus (HCoV-HL-63)
The contributors to the book are many of the experts in coronavirus virology
Summary
Some 4 years after the outbreak of SARS, this book edited by Volker Thiel tries to summarize the most recent advances in coronavirus molecular biology, vaccine development and coronavirus therapeutics, with great emphasis on SARS-CoV. The first section contains chapters that discuss the evolution and molecular biology of the Coronaviridae, often using information gained from studying group 2 coronaviruses. The second part of the book consists of chapters that review the pathogenesis of coronavirus diseases, such as those caused by SARS-CoV, feline infectious peritonitis virus (FIPV), mouse hepatitis virus (MHV) and human NL63 coronavirus (HCoV-HL-63).
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