Year-end Sale % OFF 
Abstract
Coronavirus disease 2019, the new public health emergency that originated in China, is spreading rapidly across the globe with limited tools to confine this growing pandemic. The virus, severe acute respiratory syndrome coronavirus 2, is transmitted by droplet infection from person to person. Our current understanding of the disease spectrum is limited. The proportion of infected children is significantly less compared to adults with the majority of them showing mild symptoms. More than half of symptomatic children present with fever and cough. However, the extent of asymptomatic infection in children and the role they play in community transmission is still undetermined. Although there are case reports of neonates infected with severe acute respiratory syndrome coronavirus 2, vertical transmission from infected mother to new-born is yet to be proven. The disease is confirmed by demonstration of the virus by real-time reverse transcriptase-polymerase chain reaction in respiratory secretions. Due to the lack of specific antiviral agents, we rely on infection-control measures to prevent disease spread and on supportive care for infected ones. This article has summarized the clinical characteristics of children with coronavirus disease 2019 based on published case reports.
Highlights
ETIOLOGYCoronavirus disease 2019 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), referred to as the novel coronavirus (2019-nCoV), with a high incidence of pneumonia in infected individuals
There are case reports of neonates infected with severe acute respiratory syndrome coronavirus 2, vertical transmission from infected mother to new-born is yet to be proven
It is not possible to determine the extent of infection among children, since many asymptomatic children are unlikely to be tested, and the role they play in the transmission of disease
Summary
Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), referred to as the novel coronavirus (2019-nCoV), with a high incidence of pneumonia in infected individuals. The virus has been detected in specimens like bronchoalveolar lavage fluid, sputum, nasal swabs, pharyngeal swabs, feces, and blood with decreasing frequency.[12,15] The viral load detected in the nasal swab of the asymptomatic patient was similar to that in the symptomatic patients.[16] the viral load in nasopharyngeal swabs can vary according to the disease severity, severe cases having significantly higher (~60 times) load than that of mild cases.[17] The study done by Xu Y, et al failed to demonstrate the replicationcompetent virus in fecal swabs, which is required to confirm the potential for fecal-oral transmission.[18] On contrary to this, live SARS-CoV-2 has been detected in a stool sample of a few patients.[15] According to a joint WHO-China report, the fecal-oral transmission did not appear to be a significant factor in the spread of infection.[9] the fecal-oral route of transmission is yet to be established. COVID-19.12 Prolonged fecal and nasal secretion of the virus in children has substantial implications for community spread
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
