Coronary Physiology: Basic Concepts and Clinical Applications

Abstract

This issue of Interventional Cardiology Clinics is dedicated to coronary physiology, providing an excellent overview of the basic concepts, historical advances in the field, clinical trial evidence, practical applications, and future developments. The authors are international experts in coronary physiology and have significantly contributed to the scientific progress in this space. In addition to an in-depth discussion on FFR (including its limitations and pitfalls), there is a focus on Coronary Flow Reserve in the context of assessing microvascular disease, the association of wall shear stress and plaque progression, the potential advantages of using resting pressure indices such as instant wave-free ratio, and the noninvasive evaluation of FFR derived from coronary computed tomography angiography. It is my hope that this issue will contribute to the much needed expansion of physiology measurements in routine clinical practice in an era of increasing scrutiny of coronary revascularization procedures.I would like to extend my gratitude to all authors who contributed to this issue of Interventional Cardiology Clinics. I hope that this issue provides a relevant and up-to-date overview of coronary physiology and will help implement some of these concepts into daily clinical practice. This issue of Interventional Cardiology Clinics is dedicated to coronary physiology, providing an excellent overview of the basic concepts, historical advances in the field, clinical trial evidence, practical applications, and future developments. The authors are international experts in coronary physiology and have significantly contributed to the scientific progress in this space. In addition to an in-depth discussion on FFR (including its limitations and pitfalls), there is a focus on Coronary Flow Reserve in the context of assessing microvascular disease, the association of wall shear stress and plaque progression, the potential advantages of using resting pressure indices such as instant wave-free ratio, and the noninvasive evaluation of FFR derived from coronary computed tomography angiography. It is my hope that this issue will contribute to the much needed expansion of physiology measurements in routine clinical practice in an era of increasing scrutiny of coronary revascularization procedures. I would like to extend my gratitude to all authors who contributed to this issue of Interventional Cardiology Clinics. I hope that this issue provides a relevant and up-to-date overview of coronary physiology and will help implement some of these concepts into daily clinical practice.