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Abstract
Introduction Coronary MR Angiography is a valuable tool for non-invasive assessment of coronary arteries. Presently, contrastenhanced, fat-saturated, ECG-triggered and navigatorgated 3D spoiled gradient-echo sequence is employed for whole-heart Coronary MRA at 3 T[1]. However, large static field variations at 3 T frequently result in non-uniform fat-suppression over the field-of-view (FOV), obscuring the delineation of coronary arteries. Multi-echo Dixon approaches utilizing iterative decomposition have been shown to provide robust fat-water separation even in the presence of large field inhomogeneities. In this study, an ECG-triggered navigator-gated 3D spoiled gradientecho multi-interleaved multi-echo (GRE-MEMI) pulse sequence is introduced which utilizes VARPRO[2] fatwater separation to achieve reliable fat-suppression and provides enhanced visualization of coronary arteries.
Highlights
Coronary MR Angiography is a valuable tool for non-invasive assessment of coronary arteries
Targeted right coronary artery (RCA) images were successfully acquired in all volunteers with effective fat-water separation
Conventional fatsaturation yields suboptimal fat-suppression whereas robust fat-suppression is evident in water-only images which provide clear depiction of coronary artery
Summary
Coronary MR Angiography is a valuable tool for non-invasive assessment of coronary arteries. Contrastenhanced, fat-saturated, ECG-triggered and navigatorgated 3D spoiled gradient-echo sequence is employed for whole-heart Coronary MRA at 3 T[1]. Large static field variations at 3 T frequently result in non-uniform fat-suppression over the field-of-view (FOV), obscuring the delineation of coronary arteries. Multi-echo Dixon approaches utilizing iterative decomposition have been shown to provide robust fat-water separation even in the presence of large field inhomogeneities. An ECG-triggered navigator-gated 3D spoiled gradientecho multi-interleaved multi-echo (GRE-MEMI) pulse sequence is introduced which utilizes VARPRO[2] fatwater separation to achieve reliable fat-suppression and provides enhanced visualization of coronary arteries. GRE-MEMI acquisition with inversion preparation (TI = 300 ms) was started 30 s after injection
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