Abstract

Following coronary artery ligation, retrograde flow and diastolic peripheral coronary pressure are reliable indices of each other and equally dependent on the number and size of interarterial coronary collaterals in accordance with Poiseuille's law. A quantitative anatomic AI has been derived with the use of Poiseuille's law. The AI for an individual heart represents the size and number of coronary collaterals and significantly correlates with the physiologic indices of coronary collateral development. Thus, the AI can be used as an investigative tool in indirectly assessing the functional significance of coronary collaterals, while conversely, retrograde flow and diastolic peripheral coronary pressure are indirect measurements of the anatomic development of the coronary collateral circulation.

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