Coronary artery rupture in male commercial turkeys

Abstract

Mortalities of 3% in a 1-week period and 2.5% in a 4-week period occurred in two flocks of 13-week-old to 16-week-old male turkeys, respectively. Eleven of 18 birds submitted to the laboratory for necropsy had large amounts of clotted blood in the pericardial sac and transverse bands of haemorrhage at the base of the left heart. Three other birds had clotted blood in the abdominal cavity due to rupture of the aorta. Histopathology of the hearts with haemorrhage at the base of the left heart revealed medial degeneration, necrosis and rupture of the coronary arteries. Special stains revealed decrease in elastic fibres and increase in fibrous connective tissue in the coronary arteries. Fourteen of 16 birds had a low copper concentration (<5 mg/kg wet weight) in the liver; the zinc concentration was high in one bird. Levels of heavy metals including copper and selenium in the feed were within normal ranges for poultry. No mycotoxins were detected in the feed. Tests for bacterial and viral pathogens showed no significant findings. The average weight of these turkeys at market at 16 weeks was 12.5 kg, which was considered 1.4 to 2.3 kg higher than normal. It is well known that male turkeys are prone to hypertensive angiopathy. Therefore, it is probable that higher body weights in the turkeys in conjunction with the hypertensive angiopathy and low levels of copper may have predisposed the birds for coronary artery rupture. Genetic diseases such as connective tissue disorders of the elastin and/or collagen were also considered as possible causes.