Abstract
Coronary Artery Calcium Score: Refining Risk stratification and Predicting Number Needed to Screen in Outpatients with Intermediate Risk Chest Pain
Highlights
Cardiovascular disease is considered the leading cause of death and disability worldwide but cardiovascular risk prediction remains an imprecise science
The study population consisted of 266 patients who underwent Coronary CT angiography (CCTA) and calcium scoring (CACs) score
The Number Need to Screen (NNS): our study aimed to look at the feasibility of combining Framingham risk Score (FRS) and CACs to refine risk stratification in outpatients with intermediate risk chest pain but the distribution of CAC within FRS groups was heterogeneous
Summary
Cardiovascular disease is considered the leading cause of death and disability worldwide but cardiovascular risk prediction remains an imprecise science. The Framingham risk score (FRS) is one of the most widely used scores to predict 10-year cardiovascular risk. It failed to identify many persons who were destined to have coronary events[2]. The total risk scores are very useful and should be used as the initial method of stratification, they are able to predict only 65–80% of future cardiovascular events[3]. The idea of using a noninvasive imaging test to detect early coronary atherosclerosis before it causes serious consequences is great. The Coronary CT angiography (CCTA) is nearly as good as an ICA in detecting coronary atherosclerosis but it has the associated risks of contrast material and radiation exposure[4]
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