Abstract
Objective To use coronary artery bypass graft (CABG) and autologous bone marrow mononuclear cell transplant to cure patients with heart failure caused by ischemic heart disease.Methods The autologous bone marrow mononuclear cell was gainedduring coronary artery bypass grafting operation.And intracoronary infusion of autologous stem cell transplantation was performed concomitant with CABG for chronic ischemic myocardium.The mortality and changes of left ventricular function,adverse events were evaluated.Results 40 patients were accepted the treatment of CABG and autologous bone marrow mononuclear cell transplant.One died of postoperative cerebral embolism.The operative mortality was 2.5%.No myocardial infarction,liver or renal failure,and fresh malignant arrhythmia were occurred.The left ventrical ejection fraction was raised.No change was occurred in LVEDD.Conclusion Using CABG and intracoronary infusion of autologous bone marrow mononuclear cell transplant to cure patients with congestive heart failure caused by ischemic heart disease is feasible and safe. Key words: Coronary artery bypass; Cell transplantation; Heart failure
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