Abstract

BackgroundCoronary heart disease is one of the diseases with the highest mortality rate. Due to the important position of cardiovascular disease prevention and diagnosis in the medical field, the segmentation of cardiovascular images has gradually become a research hotspot. How to segment accurate blood vessels from coronary angiography videos to assist doctors in making accurate analysis has become the goal of our research.MethodBased on the U-net architecture, we use a context-based convolutional network for capturing more information of the vessel in the video. The proposed method includes three modules: the sequence encoder module, the sequence decoder module, and the sequence filter module. The high-level information of the feature is extracted in the encoder module. Multi-kernel pooling layers suitable for the extraction of blood vessels are added before the decoder module. In the filter block, we add a simple temporal filter to reducing inter-frame flickers.ResultsThe performance comparison with other method shows that our work can achieve 0.8739 in Sen, 0.9895 in Acc. From the performance of the results, the accuracy of our method is significantly improved. The performance benefit from the algorithm architecture and our enlarged dataset.ConclusionCompared with previous methods that only focus on single image analysis, our method can obtain more coronary information through image sequences. In future work, we will extend the network to 3D networks.

Highlights

  • Coronary heart disease is one of the diseases with the highest mortality rate

  • Compared with previous methods that only focus on single image analysis, our method can obtain more coronary information through image sequences

  • Data In our work, we choose two parts of the dataset for training, one is the public Digital retinal images for vessel extraction (DRIVE) [28] dataset which is widely used for vessel detection, and the other dataset comes from the angiography video of coronary interventional surgery. 170 video clips contain clear blood vessels with contrast agents were annotated manually by medical students

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Summary

Introduction

Coronary heart disease is one of the diseases with the highest mortality rate. Due to the important position of cardiovascular disease prevention and diagnosis in the medical field, the segmentation of cardiovascular images has gradually become a research hotspot. How to segment accurate blood vessels from coronary angiography videos to assist doctors in making accurate analysis has become the goal of our research. Cardiovascular disease, especially coronary sclerotic heart disease, known as coronary heart disease, is one of the diseases with the highest mortality rate Doctors diagnose these cardiovascular diseases by directly observing angiographic images with their eyes. According to experience, they make a qualitative judgment on the patient’s condition. With the extension of the blood vessels, the blood vessels gradually become thinner, and there is vascular stenosis caused by the blockage. The shape or grayness of some tissues is similar to that of the blood vessels, which makes it difficult to extract blood vessels

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