Abstract

COVID-19, a rapidly spreading new strain of coronavirus, has affected more than 150 countries and received worldwide attention. The lack of efficacious drugs or vaccines against SARS-CoV-2 has further worsened the situation. Thus, there is an urgent need to boost up research for the development of effective therapeutics and affordable diagnostic against COVID-19. In this time of health crisis, it is the duty of scientific research community to provide alternative, effective and affordable strategies to vaccinate human bodies against viral infections-COVID-19 based on focused experimental approaches. Corona virus (CoV) is forward RNA virus on its surface, containing stick-shaped spikes. It is an undesirable broad genome of RNA, with an indefinite replication system. In mammals, birds, pigs and chickens, corona virus cause various infections. This triggers the pathogens of the upper respiratory tract, which can lead to death due to breathing illnesses. In this article the author briefly justify sudden occurrence of this highly pathogenic extreme lung disease and recently discovered in Middle East respiratory syndrome corona virus (MERS-CoV). This is review article are awareness about the CoVID-19 infection and its out break throughout the world. In this article brief history about life cycle, pathogenecity and transmittance of corona virus given.

Highlights

  • In 1960, the very first outbreak of corona virus was identified with cold symptoms

  • Corona viruses are single standard RNA viruses covered with glycoprotein covering that is club shaped

  • Considering the bats appears to be notable reservoir for this disease, which will important to know whether remain carefully separate from medically noticeable illnesses and work, hard to contaminate them

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Summary

History of Origin

In 1960, the very first outbreak of corona virus was identified with cold symptoms. Numerous studies were reported in 2003 with evidence of expanding the corona to different states such as Hong Kong, United States, Singapore, Thailand and China. Several reports of extreme acute respiratory syndrome induced by corona were recorded in 2003 and their death rate around 1000 patient in March to June 2003. COVID-19 was first detected and identified from the monopoly on the pneumonia belongs to China, Wuhan [5,6]. Major sudden occurrence was found in Hong Kong, Singapore and China and in many countries of Southeast Asia and in North America Spreading of this disease due to high level of social contact through community. After a long time again in city of Wuhan (China) outbreak of this disease occurred in December 2019. 80,824 (54.02%) nCoVD-19 confirmed cases are found and its rate continuously increased

Morphology of Corona Virus
Classification
Genomic Organization
Virion Structure
Findings
Conclusion

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