Abstract

Corneal surface reconstruction - a short review

Highlights

  • M e diseases, stem cells residing in its rim called c "limbus" are stimulated to multiply to support R growth of new epithelial cells over its surface

  • The use of amniotic membrane transplantation (AMT) to treat ocular surface abnormalities was first reported by Graziella Pellegrini, chief of stem cell laboratory at Giovanni Paolo Hospital in Venice, Italy, who was the first to demonstrate the limbal stem cell transplant in 1997

  • The role biopsy in the laboratory using cell cultures that could be transplanted to the affected eye have been developed,4, 5 of AMT in ocular disorders has been recently re-evaluated by Schwab and coworkers.[11]

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Summary

Introduction

M e diseases, stem cells residing in its rim called c "limbus" are stimulated to multiply to support R growth of new epithelial cells over its surface. The role biopsy in the laboratory using cell cultures that could be transplanted to the affected eye have been developed ,4, 5 of AMT in ocular disorders has been recently re-evaluated by Schwab and coworkers.[11] Human amniotic membrane (HAM) is used as construct to assess the risks and reviewed 20 a scaffold for both culturing the human limbal published reports of human trials conducted epithelial cells and for ocular surface between 1996 and 2005 in a report suggesting reconstruction with the cultured limbal that the currently used transplant procedures epithelial cells.

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