Abstract
A 47-year-old woman with history of multiple sclerosis on ocrelizumab was referred for evaluation of leukoplakic placoid inferior limbal-corneal lesion of the left eye (A). Anterior-segment OCT demonstrated a well-circumscribed intraepithelial mass (B). The conjunctiva and eyelids were unremarkable. The lesion did not respond to topical interferon-alpha for presumed ocular surface squamous neoplasia, so the mass underwent excision. Histopathology revealed a thickened limbal-corneal epithelium with hypergranulosis (arrow), surface keratinization (asterisk), and molluscum contagiosum bodies (arrowheads) (C, hematoxylin-eosin, 400×). Further questioning disclosed a history of multiple self-limited eyelid margin nodules, suggestive of cutaneous molluscum contagiosum (Magnified version of Figure A-C is available online at www.aaojournal.org).
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