Abstract
To compare human central corneal, limbal and bulbar conjunctival epithelial thickness in vivo using an Optical Coherence Tomographer (OCT). Thirteen healthy human subjects participated in this study. An OCT (Carl Zeiss, Meditec, Dublin, CA) was used to image central cornea, temporal corneo-scleral limbus and bulbar conjunctiva of the left eye. Two images were taken at each location. Thirty central measurements were averaged from each image for quantifying epithelial thickness. In addition to the central cornea and limbal region, a band corresponding to bulbar conjunctival "epithelium" is apparent in OCT images, with respective thicknesses of 54.7 +/- 1.9 microm (mean +/- SD), 79.6 +/- 7.4 microm and 44.9 +/- 3.4 microm that are statistically significant different (repeated measures analysis of variance p < 0.01, post hoc test shows all p < 0.01). This study demonstrates that it is possible to image the epithelial tissue in humans in vivo using optical coherence tomography, and in these subjects, the corneo-limbal epithelium is the thickest, while the bulbar conjunctival epithelium is the thinnest and the corneal epithelium has intermediate thickness.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
