Corneal Hysteresis in Adult Indian Population

Abstract

Purpose: To evaluate corneal hysteresis (CH) and to study its inter-ocular variability along with its association with gender and age using Ocular Response Analyzer (ORA) among healthy adult Indian population. Methods: This prospective, cross-sectional, observational study was conducted at a tertiary eye care centre in a medical university in India between July and December 2020. 300 healthy participants in age group between 18 to 60 years were recruited from amongst the residents, staff and patients coming for routine examination in Ophthalmology department. Participants with history of systemic/ocular disease, ocular surgery, pregnancy or spherical equivalent refraction >±1D were excluded from study. CH and corneal compensated intra-ocular pressure (IOP-cc) was assessed using ORA. Statistical analysis was done to calculate mean CH in study population. Inter-ocular and gender-wise variability in mean CH was analysed using independent-t test. Pearson correlation coefficient was calculated to study correlation of CH between eyes and with age, gender, IOP-cc and central corneal thickness (CCT). Results: 162 males and 134 females were recruited. The mean age was 37.5±11 years and mean CH in overall study population, males and females were 10.57±1.12, 10.25±0.90, 10.96±1.22 mm Hg. No significant difference in CH, IOP-cc and CCT was observed between eyes. A strong positive correlation was observed in CH between eyes (r=0.75, p<0.001). Conclusions: Mean CH among healthy Indian adult is 10.57±1.12 mm Hg. CH values are higher among females compared to males. CH values between the two eyes in normal individuals are coherent and positively correlated.