Abstract
We present the cases of three patients with colorectal cancer who were treated with combined chemotherapy regimens containing S-1. Eye disorders developing as adverse effects of anticancer drugs can be resolved by discontinuation of the causative anticancer drugs, although the disorders may be irreversible in some cases, thereby necessitating early diagnosis and prompt treatment. Medical oncologists must pay attention to eye disorders caused by the anticancer drug S-1. It is necessary to refer patients with eye disorders suspected to be caused by an anticancer drug immediately to an ophthalmologist, because of the possibility of injury to the cornea and/or lacrimal duct.
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