Abstract
Collagen cross-linking (CXL) is a new horizon in the treatment of corneal diseases.The corneal stroma is the thickest part of the cornea and is mainly composed of collagen fibrils,charged with stromal maintenance and wound healing. CXL by using UV rays and riboflavin could actas a photo mediator to inactivate pathogens in plasma, platelets, and red blood cells. Riboflavin alsoinduces a change in properties of the collagen and has a stiffening effect on the corneal stroma,which stabilizes it and increases its resistance to enzymatic bacteria degradation avoiding theprogression of corneal melting this study aimed to assess the efficacy and safety of corneal collagencross-linking (CXL) in the management of infectious keratitis.
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