Abstract
Trisomy 8 mosaicism is a rare chromosomal disorder with multisystemic abnormalities.1 Clinical features include characteristic facies; thick ears; abnormal dermatoglyphic patterns; mental retardation; and cardiovascular, genitourinary, and musculoskeletal malformations.2 The most commonly reported ocular manifestations are corneal abnormalities, cataract, iris heterochromia, and strabismus.3,4 We report a case of trisomy 8 mosaic syndrome with bilateral asymmetric corneal opacities. Histopathology of the corneal button obtained at the time of penetrating keratoplasty was consistent with a choristoma by inclusion of fibroblastic and glandular tissue. Surgical treatment permitted amblyopia therapy.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
