Co-relation of multidetector CT scan based preoperative staging with intra-operative findings and post-operative histological staging of colorectal carcinoma

Abstract

AimTo assess the accuracy of CT scan in preoperative staging, to correlate preoperative findings with operative findings and with post-operative histopathological findings of colorectal carcinoma. MethodsTwenty-six diagnosed cases of colorectal carcinoma were included in the study. They were evaluated preoperatively by 64 slice multidetector CT (MDCT) scan. Intra-operative evaluation was done at the time of surgery. Post-operative evaluation was based on detailed histological examination by experienced pathologist. Data was statistically assessed by SPSS software (version 14.0) and the correlation was deduced from “kappa” value and “P”. ResultsThe correlation of CT scan staging is significant (P ≤ 0.0001) when compared to intra-operative staging. MDCT findings correlated with intra-operative findings in terms of site of lesion (P < 0.001), serosa involvement (P < 0.0001), involvement of circumference (P < 0.0001), pericolic/perirectal fat involvement (P < 0.009) and assessment of lymph nodes (P = 0.004). In estimating size of lesion, it also correlated with the intra-operative findings (44 %). MDCT findings correlated with histopathological findings in terms of site of lesion (P < 0.001), circumference involved (P < 0.0001), serosal involvement (P = 0.018) and size of lesion. The CT findings did not correlated significantly in terms of pericolic/ perirectal fat involvement (P = 0.127) and assessment of lymph nodes (P = 0.68). ConclusionMultidetector CT scan can be useful in the preoperative assessment of patients with colorectal carcinoma as a means for assisting surgical planning.