Abstract
The high surface area per unit volume and core-shell configuration of electrospun nanofiber mat has a potential for drug delivery applications. Co-axial electrospinning technique resolves the limitation in the traditional transdermal drug delivery materials allowing to load a larger concentration of therapeutic agents per unit mass of the polymer. Encapsulating the drug in the fiber core provides protection and prolonged drug release. In the present study mats of core-shell PVA/PVP-FeOOH nanofibers were successfully formed by the coaxial electrospinning process for the first time. The visible light responsive FeOOH drug carrier material was incorporated in fiber core to provide non-invasive drug release on demand. The prepared materials posses visible light triggered release of organic methylene blue molecules.
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