Abstract
IntroductionThe blood stasis pattern in Chinese and Korean traditional Medicine is characterised by stagnation, including extravasated blood and sluggish blood circulation or viscous or congested blood, all of which may become pathogenic factors. Blood stasis is associated with chronic and incurable disease, such as pain, infertility, cancer and health reducing conditions caused by stress, which are not relieved with modern medicine. The aim of the study is to establish a modern concept of blood stasis, develop diagnostic tools and diagnostic indices for blood stasis, identify biological indices related to blood stasis. MethodsThis community-based, multi-centre trial is designed as an observational study. Data will be collected in order to standardise blood stasis diagnosis in Korea. Patients will be admitted to one of the following 7 hospitals participating in this study: Kyung Hee Oriental Medical Centre, Kyung Hee University Oriental Hospital at Gangdong, Wonkwang Oriental Medical Hospital, Jaseng Hospital of Oriental Medicine, Cha Medical Centre, Pusan National University Korean Medicine Hospital and Dongguk University Ilsan Oriental Hospital. A total of 1400 participants will be recruited through local advertising and doctor referrals from hospitals. At each site, 200–280 participants will be recruited. Ethics and disseminationAll of the research aims, the study design, and the specific methods in this study have been approved by the Institutional Review Boards (IRB) of all seven of the participating hospitals. Additionally, the study was approved by the IRB of the Korean Institute of Oriental Medicine. Trial registrationCRIS No. KCT 0000916
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