Abstract
AbstractA variety of novel copper complexes were synthesized and characterized of the formulae [Cu(L1)(OAc)], [CuL2(H2O)], [CuL3(H2O)], [CuL4(OAc)], [CuL5(H2O)] [CuL6], [CuL7], [CuL8](OAc) and [CuL9], where L1L9 represents Schiff base ligands [derived by the condensation of 5‐hydroxyflavone with 4‐aminoantipyrine (L1), o‐aminophenol (L2), o‐aminobenzoic acid (L3), o‐aminothiazole (L4), thiosemicarbazide (L5), 4‐aminoantipyrine‐o‐aminophenol (L6), 4‐aminoantipyrine‐o‐aminobenzoic acid (L7), 4‐aminoantipyrine‐o‐aminothiazole(L8) and 4‐aminoantipyrine‐thiosemicarbazide (L9)]. The spectral and magnetic results of the Cu(II) complexes exhibit square planar geometry. The DNA binding properties of copper complexes were studied by using electronic absorption spectra, viscosity and thermal denaturation experiments. The results show that the complexes were interacting with calf thymus (CT DNA). The in vitro antimicrobial activities of the investigated compounds were tested against the bacterial species and fungal species. Superoxide dismutase and antioxidant activities of the copper complexes have also been studied. Copyright © 2011 John Wiley & Sons, Ltd.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have