Abstract
In grape and wine production, one of the main relevant and recurrent diseases is downy mildew caused by the fungus (Plamospara viticola). It is frequently present in wine production worldwide, with a significant high annual incidence in some regions. Since the discovery of Bordeaux mixture (copper sulphate and lime) in the 1880’s, many formulations based on copper (Cu) have been developed and used in viticulture production. https://coppereplace.com/.
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